The Afro-German songstress started her budding career doing backup and support vocals for soul and reggae bands such as Cultural Roots and Family Affair. Her big break occurred when she was called into the city of Stuttgart to lay down vocals for established electronica and hip-hop producers DJ Thomilla and Tiefschwarz on the international dance hit "Music" in 1999. The lead member of German rap group Freundeskreis, Max Herre, also happened to be looking for a female vocalist in order to accompany him on the song "Mit Dir" ("With You"), which became a Top Five hit on the German charts the same year. Her relationship with Herre (whom she wound up marrying) enabled her to sign with the Sony subsidiary Four Music Records.
Mostly in German, Mamani debuted Denalane's singing talents in May 2002. Produced by Herre, the album blended traditional R&B with jazz, Afrobeat, and South African folk music; moreover, it notably contained horn arrangements and live flügelhorn by the illustrious South African jazz musician Hugh Masekela. Mamani, which debuted at number eight on the German charts, helped put definition to "German soul" within the world music arena. Afterward, she began receiving exposure in the U.S. from her guest vocals on the remix of the single "Go!" by American rapper Common. The song grabbed the attention of prolific arrangers and neo-soul mainstays like James Poyser, Jeff Bradshaw, Larry Gold, and a host of others who all contributed to Denalane's 2006 album Born & Raised. Recorded in Philadelphia, the LP was much more accessible for English speakers as well as hip-hop heads, boasting appearances from MCs Lupe Fiasco and Raekwon. It debuted at number two on the German album chart and broke into Billboard's European Top 100 album chart. ~ Cyril Cordor, All Music Guide